Subcutaneous tunnelling versus conventional insertion of peripherally
inserted central catheters in hospitalised patients (TUNNEL‑PICC): a randomised controlled trial
Given increasing use of peripherally inserted central catheter (PICC), the interest for the prevention of central-line associated blood stream infection (CLABSI) has increased. Subcutaneous tunneling for central venous catheter was well established method for protection from the CLABSI. We aimed to evaluate whether subcutaneous tunnel could reduce the incidence of CLABSI in PICC placement.
To determine effect of subcutaneous tunneling in PICC placement on CLABSI rate.
To evaluate subcutaneous tunneling associated adverse events
Tunneled PICC is superior to conventional PICC placement regarding central-line associated bloodstream infection in hospitalized patients
Multi-institutional, superiority, pragmatic, assessor blinded, parallel-group, randomized trial
> 18 years of age hospitalized individuals who required PICC for medical needs.
To evaluate whether adding subcutaneous tunneling in PICC placement reduce the rate of CLABSI compared to the conventional method.
Site: Five educational and referral hospitals in Seoul and metropolitan cities, Republic of Korea.
Participants: 1301 patients
From November 16, 2020 to March 13, 2023
Clinical Research Information Service (CRiS, No. KCT0005521).
